Danny Glover

Silas (segment "Long Black Song")

Wesley Snipes

George Du Vaul (segment "The Boy Who Painted Christ Black")

Lorraine Toussaint

Philomena (segment "The Reunion")

Tate Donovan

David (segment "Long Black Song")

Norman D. Golden II

Aaron (segment "The Boy Who Painted Christ Black")

Susanna Thompson

Beth Ann (segment "The Boy Who Painted Christ Black")

Jasmine Guy

Elna Du Vaul (segment "The Boy Who Painted Christ Black")

Tina Lifford

Sarah (segment "Long Black Song")

Carl Lumbly

Cal (segment "The Boy Who Painted Christ Black")

Bennet Guillory

Willie (segment "The Boy Who Painted Christ Black")

Danny Kamin

Mr. Harper (segment "Long Black Song")

Rae'Ven Larrymore Kelly

Lara (segment "The Boy Who Painted Christ Black")

Timothy Carhart

Prof. Daniel (segment "The Boy Who Painted Christ Black")

Summer Ross Jefferson

Young Philomena #1 (segment "The Boy Who Painted Christ Black")

Vanessa Bell Calloway

Miss Williams (segment "The Boy Who Painted Christ Black")

Winter Elaine Jefferson

Young Philomena #2 (segment "The Boy Who Painted Christ Black")

Amanda Addison

Young Beth Ann (segment "The Boy Who Painted Christ Black")

Kevin Jamal Woods

Clyde (segment "The Boy Who Painted Christ Black")

Ruth Beckford

Mrs. McClaren (segment "The Boy Who Painted Christ Black")

Yolanda King

Mrs. Crawford (segment "The Boy Who Painted Christ Black")